Aminoindane compounds and use thereof in treating pain

US8865741B2 · kind B2 · utility

Assignee

• Asana BioSciences, LLC · US

Inventors

• Scott K. Thompson · Phoenixville, US
• Tony Priestley · West Chester, US
• Roger Smith · Madison, US
• Ashis Saha · Stow, US
• Sonali Rudra · Sherghati, IN
• Arun Kuma Hajra · Sherghati, IN
• Dipanwita Chatterjee · Sherghati, IN
• Carl Henry Behrens · Wilmington, US
• Yigang He · Daguantang, CN
• Hui Li · Santa Clara, US

Key dates

• Filing date: Feb 18, 2012
• Grant date: Oct 21, 2014
• Expiry date: Feb 18, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application provides novel aminoindane compounds and methods for preparing and using these compounds. These compounds are useful in treating pain and/or itch in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) or (II) and a TRPV1 receptor activator. In one embodiment, the TRPV1 receptor activator is lidocaine.