Patent · US Active

Mutant epidermal growth factor polypeptides with improved biological activity and methods of their making and use

US8865864B2 · kind B2 · utility

0Cited by

2References

1Claims

0Family size

Assignee

The Board of Trustees of the Leland Stanford Junior University · US

Inventors

Jennifer R. Cochran · Stanford, US
Bertrand Howyen Lui · Menlo Park, US
Jennifer Lynn Lahti · Rue de l'Église, US
James R. Swartz · Menlo Park, US
Bob Chen · Diamond Bar, US
Cheuk Lun Leung · Cambridge, US

Key dates

Filing date	Aug 27, 2012
Grant date	Oct 21, 2014
Priority date	—
Expiry date	Aug 27, 2032

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/485
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Compositions that are EGF polypeptides that possess improved biological activity as compared to the biological activity exhibited by wild-type EGF are provided. Also provided are methods for the preparation of these mutants, methods for the use of these mutants, methods for rationally designing new polypeptide mutants, and methods for screening mutants polypeptides to identify novel EGF mutants with desirable biological activities.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.