Methyltetrazole sulfides and sulfones
US8865900B2 · kind B2 · utility
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9Claims
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Assignee
Inventor
Key dates
| Filing date | Jan 13, 2012 |
| Grant date | Oct 21, 2014 |
| Priority date | — |
| Expiry date | Jan 13, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D419/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process for the preparation of a 1-methyl-1H-tetrazole-5-thio derivative comprising reaction of a halomethyl substrate with 1-methyl-H-tetrazole-5-thiol to obtain a thio-ether compound, and oxidizing the thio-ether compound to the corresponding sulfone. In case of a chiral halomethyl substrate, the resulting chiral diol sulfone derivative is suitable as a building block for statin type compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.