Patent · US Active

Stabilizing formulations

US8871201B2 · kind B2 · utility

13Cited by

5References

17Claims

0Family size

Assignee

Wyeth, LLC · US

Inventors

Li Li · Stanford, US
Angela Kantor · Pepperell, US
Shannon Macmillan · Hollis, US

Key dates

Filing date	Aug 12, 2005
Grant date	Oct 28, 2014
Priority date	—
Expiry date	Mar 10, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/24
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Formulations are described that are suitable for storage of proteins, such as antibodies, over a relatively broad range of protein concentrations, pH, and buffer types. Also described are methods of storing a protein and methods of identifying a suitable formulation for storage of a specific protein. In general, a formulation contains low to no surfactant, no to relatively low salt concentrations, and requires a relatively low buffer concentration.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.