Patent · US Active

Enhanced deposition of chromogens

US8871442B2 · kind B2 · utility

3Cited by

21References

33Claims

0Family size

Assignee

Ventana Medical Systems, Inc. · US

Inventors

Eric May · Oro Valley, US
Adrian E. Murillo · Tucson, US
Jerome W. Kosmeder · Tucson, US

Key dates

Filing date	Dec 28, 2011
Grant date	Oct 28, 2014
Priority date	—
Expiry date	Apr 8, 2032

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/581
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

This disclosure relates to compositions that enhance the deposition of detectable moieties on tissue samples, methods utilizing these compositions and kits including these compositions. The compositions include a deposition enhancer having a formulawhere R1, R2, R3, and R4 are independently selected from aliphatic, aryl, halogen, a heteroatom-containing moiety, and hydrogen; R1 and/or R3 can be bound to R2 to form a fused, aromatic ring system; R5 is selected from a heteroatom-containing moiety; A is selected from, a carbon atom, a heteroatom, other than sulfur, and any combination thereof; n is 1-5, an enzyme, a specific binding moiety and a detectable moiety.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.