Patent · US Active

Neprilysin inhibitors

US8871792B2 · kind B2 · utility

51Cited by
21References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 6, 2013
Grant dateOct 28, 2014
Priority date
Expiry dateJun 6, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/65312
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

In one aspect, the invention relates to compounds having the formula X:where Ra, Rb, R2, R7, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds described herein are prodrugs of compounds having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.