Metaxalone cocrystals
US8871793B2 · kind B2 · utility
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24Claims
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Assignee
Inventors
Key dates
| Filing date | Dec 22, 2010 |
| Grant date | Oct 28, 2014 |
| Priority date | — |
| Expiry date | Jun 24, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C65/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to improvements of the physiochemical and/or the pharmaceutical properties of metaxalone. Disclosed herein are several new cocrystals of metaxalone, including: a 1:1 metaxalone adipic acid cocrystal, a 1:0.5 metaxalone fumaric acid cocrystal, a 1:1 metaxalone salicyclic acid cocrystal, a 1:0.5 metaxalone succinic acid cocrystal, and a 1:0.5 metaxalone maleic acid cocrystal. The therapeutic uses of these metaxalone cocrystals are described as well as therapeutic compositions containing them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.