Design, synthesis and use of synthetic nucleotides comprising charge mass tags
US8871921B2 · kind B2 · utility
12Cited by
1References
28Claims
0Family size
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Inventor
Key dates
| Filing date | Sep 3, 2009 |
| Grant date | Oct 28, 2014 |
| Priority date | — |
| Expiry date | May 10, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6816
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Embodiments of the present disclosure relate generally to reporter compositions which are synthetic nucleotides that comprise nucleotides with a high charge mass moiety attached thereto via a linker molecule. The linker molecules can vary in length in part to enable the high charge mass moiety to extend out from a DNA polymerase complex so that polymerization may not be influenced.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.