Patent · US Active

Method for manufacturing of quinoline-3-carboxamides

US8871936B2 · kind B2 · utility

0Cited by

6References

18Claims

0Family size

Assignee

Active Biotech AB · SE

Inventors

Lillemor Maria Bock · Karlskoga, SE
Pär Holmberg · Bodafors, SE
Karl Jansson · Dalby, SE

Key dates

Filing date	Jul 7, 2011
Grant date	Oct 28, 2014
Priority date	—
Expiry date	Jul 7, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P37/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method for preparing a compound of formula (I) by reacting the appropriate alkyl ester and an aniline derivative, in a refluxing mixture containing an aliphatic solvent or a mixture of aliphatic solvents having a boiling point in the range of 68-191° C.; condensing vapors of the refluxing mixture; treating the condensed vapors with an alcohol scavenging agent or a mixture of alcohol scavenging agents; and returning the condensed vapors back to the reaction mixture.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.