In vitro test system for viral infections

US8876903B2 · kind B2 · utility

Assignee

• Fraunhofer-Gesellschaft zur förderung der angewandten Forschung e.V. · DE

Inventors

• Anke BURGER-KENTISCHER · Stuttgart, DE
• Ina Hogk · Waiblingen, DE
• Doris Finkelmeier · Fellbach, DE
• Heike Walles · Sindelfingen, DE
• Steffen Rupp · Stuttgart, DE
• Michaela R. Kaufmann · Fox Point, US

Key dates

• Filing date: Jun 2, 2011
• Grant date: Nov 4, 2014
• Expiry date: Nov 14, 2032

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/035
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention relates to a multi-layered biological in vitro tissue containing: dermis layer, containing a collagen biomatrix with fibroblasts embedded therein and epidermis layer, containing epithelial cells. It is provided that latently virally infected neuronal cells are integrated at least into the dermis layer.