Patent · US Active

Polyanionic multivalent macromolecules for intracellular targeting of proliferation and protein synthesis

US8877171B2 · kind B2 · utility

0Cited by

2References

24Claims

0Family size

Assignee

MIVENION GMBH · DE

Inventors

Kai Licha · Berlin, DE
Michael Schirner · Berlin, DE
Pia Welker · Berlin, DE
Rainer Haag · Berlin, DE
Marie Weinhart · Berlin, DE
Florian Paulus · Berlin, DE

Key dates

Filing date	Jan 31, 2011
Grant date	Nov 4, 2014
Priority date	—
Expiry date	Jan 31, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08G83/003
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates generally to methods and compositions for targeting of intracellular molecules involved in proliferation and protein synthesis of activated cells using polyanionic multivalent macromolecules. In particular aspect, multiple sulfate groups linked to polyol are specifically targeted to the cytoplasm and nucleus of proliferating and activated cells. The invention further comprises novel polyanionic macromolecular compounds and formulations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.