Patent · US Active

Nanoparticles of cerium oxide targeted to an amyloid-beta antigen of Alzheimer's disease and associated methods

US8877207B2 · kind B2 · utility

2Cited by

43References

11Claims

0Family size

Assignees

University of Central Florida Research Foundation · US
University of L'Aquila · IT

Inventors

Annamaria Cimini · L'Aquila, IT
Barbara D'Angelo · L'Aquila, IT
Soumen Das · Survanagiri, IN
Sudipta Seal · Oviedo, US

Key dates

Filing date	Jul 18, 2011
Grant date	Nov 4, 2014
Priority date	—
Expiry date	Jul 18, 2031

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB82Y5/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed is a composition immunologically targeted to Alzheimer's disease (AD), the composition containing amine functionalized nanoparticles of Cerium oxide coated with polyethylene glycol and bearing an antibody specific for an amyloid-beta antigen associated with AD. The invention also includes a medication manufactured with the targeted nanoceria particles and methods of treatment by administering the targeted nanoceria particles to patients in need thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.