Bacterial cells having a glyoxylate shunt for the manufacture of succinic acid
US8877466B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 22, 2009 |
| Grant date | Nov 4, 2014 |
| Priority date | — |
| Expiry date | Feb 24, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/46
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is concerned with bacteria for the production of succinic acid. Specifically, the invention relates to a bacterial cell of the genus Pasteurella comprising a heterologous polypeptide having isocitrate lyase activity and a heterologous polypeptide having malate synthase activity. Further, the present invention contemplates a polynucleotide comprising a nucleic acid encoding a polypeptide having isocitrate lyase activity and a nucleic acid encoding a polypeptide having malate synthase activity. Finally, the present invention relates to the use of a bacterial cell of the invention for the manufacture of succinic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.