Patent · US Active

Bacterial cells having a glyoxylate shunt for the manufacture of succinic acid

US8877466B2 · kind B2 · utility

1Cited by
11References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 22, 2009
Grant dateNov 4, 2014
Priority date
Expiry dateFeb 24, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P7/46
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention is concerned with bacteria for the production of succinic acid. Specifically, the invention relates to a bacterial cell of the genus Pasteurella comprising a heterologous polypeptide having isocitrate lyase activity and a heterologous polypeptide having malate synthase activity. Further, the present invention contemplates a polynucleotide comprising a nucleic acid encoding a polypeptide having isocitrate lyase activity and a nucleic acid encoding a polypeptide having malate synthase activity. Finally, the present invention relates to the use of a bacterial cell of the invention for the manufacture of succinic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.