Substituted pyrrolo[2,3-B]pyridines as MLK inhibitors
US8877772B2 · kind B2 · utility
18Cited by
45References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 25, 2009 |
| Grant date | Nov 4, 2014 |
| Priority date | — |
| Expiry date | Nov 25, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are compounds having an inhibitory effect on Mixed Lineage Kinases, having a structural Formula,Also provided are pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by Mixed Lineage Kinase inhibition. Also provided are methods of treatment of neuropsychiatric disorders which comprise the inhibition of Mixed Lineage Kinases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.