Patent · US Active

Substituted carbamoylcycloalkyl acetic acid derivatives as NEP

US8877815B2 · kind B2 · utility

0Cited by

3References

18Claims

0Family size

Assignee

Novartis AG · CH

Inventors

Rajeshri Ganesh Karki · Somerville, US
Toshio Kawanami · Belmont, US
Gary Michael Ksander · Carmel, US
Qian Liu · Suzhou, CN
Muneto Mogi · Waltham, US
Nikolaus SCHIERING · Weil am Rhein, DE
Robert Sun · Natick, US

Key dates

Filing date	Nov 10, 2011
Grant date	Nov 4, 2014
Priority date	—
Expiry date	Dec 5, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2601/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a compound of formula I;or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, B, X, m and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides pharmaceutical composition of compounds of the invention, and a combination of pharmacologically active agents and a compound of the invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.