Non-contrast-enhanced 4D MRA using compressed sensing reconstruction

US8879852B2 · kind B2 · utility

Assignee

• Siemens Aktiengesellschaft · DE

Inventors

• Ti-chiun Chang · Plainsboro, US
• Mariappan S. Nadar · Plainsboro, US
• Jens Gühring · Monmouth Junction, US
• Michael Zenge · Nuremberg, DE
• Kai Tobias Block · Nuremberg, DE
• Peter Schmitt · Erlangen, DE
• Edgar Mueller · Heroldsbach, DE

Key dates

• Filing date: Oct 28, 2011
• Grant date: Nov 4, 2014
• Expiry date: Oct 28, 2031

Classification

• Technology area (CPC G): Physics
• CPC primary: G01R33/56545
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A reconstructed image is rendered of a patient by a processor from a set of undersampled MRI data by first subtracting two repetitions of the acquired data in k-space to create a third dataset. The processor reconstructs the image by minimizing an objective function under a constraint related to the third dataset, wherein the objective function includes applying a Karhunen-Loeve Transform (KLT) to a temporal dimension of data. The objective function under the constraint is expressed as arg minf{∥φ(f)∥1 subject to ∥Af−y∥2≦ε}. The reconstructed image is an angiogram which may be a 4D angiogram. The angiogram is used to diagnose a vascular disease.