Tissue-derived tissuegenic implants, and methods of fabricating and using same

US8883210B1 · kind B1 · utility

Assignee

• Musculoskeletal Transplant Foundation · US

Inventors

• Katherine G. Truncale · Fryeburg, US
• Arthur A. Gertzman · Bound Brook, US
• Yen-Chen Huang · East Brunswick Township, US
• Eric J. Semler · Piscataway, US
• Evangelia Chnari · Scotch Plains, US
• Anouska Dasgupta · New Brunswick, US
• Judith I. Yannariello-Brown · Somerville, US
• Terri Riley · Linden, US

Key dates

• Filing date: May 16, 2011
• Grant date: Nov 11, 2014
• Expiry date: Jul 11, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2533/90
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure provides implants containing a plurality of particles containing at least one population of viable tissuegenic cells adherent to and resident in the growth-conductive matrix or at least viable population of tissuegenic cells caused to be in contact with the growth-conductive matrix; methods to fabricate implants; methods of fabricating the implants; and use of the implants in tissue repair.