Pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma containing an extract of Decaspermum fruticosum
US8883226B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 7, 2012 |
| Grant date | Nov 11, 2014 |
| Priority date | — |
| Expiry date | Feb 7, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma comprising the extract of Decaspermum fruticosum as an active ingredient. The extract of Decaspermum fruticosum of the present invention inhibited the increase of eosinophils in bronchoalveolar lavage fluid of the ovalbumin induced asthma animal model, had the activity of inhibiting the secretions of immunoglobulin and chemokine (Eotaxin) in bronchoalveolar lavage fluid and blood, and inhibited the secretions of NO and TNF-α in macrophages. Therefore, the extract of Decaspermum fruticosum of the present invention can be effectively used as an active ingredient of a pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma, and of a health functional food for the prevention and improvement of inflammatory disease or asthma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.