Patent · US Active

Use of therapeutically effective lipids and method for producing organ-/tissue-specific therapeutically effective lipids

US8883426B2 · kind B2 · utility

0Cited by

1References

7Claims

0Family size

Assignee

Pat Inc. · DE

Inventor

Wolfgang Stremmel · Heidelberg, DE

Key dates

Filing date	Mar 20, 2008
Grant date	Nov 11, 2014
Priority date	—
Expiry date	Apr 19, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P1/16
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The use of therapeutically active lipids for organ/tissue-specific enrichment for the treatment of inflammatory, ischemic or degenerative disorders and/or for stimulating a regeneration is arranged and developed such that the lipids are bound on application to carrier molecules for which cell-specific uptake systems in the cells of the organs and/or tissue exist. In addition, a method of producing organ/tissue-specific therapeutically active lipids for treatment of inflammatory, ischemic or degenerative disorders and/or stimulation of a regeneration, in particular for treating inflammatory liver disorders, is claimed, which is arranged and developed such that lysophosphatidylethanolamine (LysoPE) is coupled to the carboxyl group of ursodeoxycholate (UrsoDOCA) converted to an ester to give a LysoPE-DOCA compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.