Inhibitors of Bruton's tyrosine kinase
US8883435B2 · kind B2 · utility
77Cited by
22References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 27, 2008 |
| Grant date | Nov 11, 2014 |
| Priority date | — |
| Expiry date | Dec 24, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are irreversible kinase inhibitor compounds, methods for synthesizing such irreversible inhibitors, and methods for using such irreversible inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate irreversible inhibitor of a protein, including a kinase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.