Patent · US Active

Process for production of cis-4-hydroxy-L-proline

US8883459B2 · kind B2 · utility

6Cited by
1References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 19, 2013
Grant dateNov 11, 2014
Priority date
Expiry dateAug 19, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y114/11002
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Development of a method of economically and efficiently producing cis-4-hydroxy-L-proline. The present invention provides L-proline cis-4-hydroxylase. This enzyme may be derived from Lotus corniculatus rhizobia, Mesorhizobium loti or Medicago sativa rhizobia, Sinorhizobium meliloti. The present invention provides a method of producing cis-4-hydroxy-L-proline from L-proline by using this enzyme. The present invention provides a recombinant vector containing a polynucleotide encoding the enzyme and a transformant containing the vector.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.