Detection of antibodies
US8883517B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Sep 14, 2010 |
| Grant date | Nov 11, 2014 |
| Priority date | — |
| Expiry date | Sep 14, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/561
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a method of detecting a target antibody, particularly a target autoantibody, in a sample, using a small molecule fluorophore-labelled target antigen, or a functional fragment, functional variant or functional derivative thereof that specifically binds to the target antibody. Detection is typically carried out using immunodiffusion or immunoelectrophoresis. The invention also relates to methods of diagnosing disease, particularly autoimmune disease, using small molecule fluorophore labelled target antigens and autoantigens. Small molecule fluorophore labelled target antigens, including autoantigens, are also disclosed, as are uses such.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.