Patent · US Active

Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions

US8883800B2 · kind B2 · utility

28Cited by

108References

15Claims

0Family size

Assignee

Boehringer Ingelheim International GmbH · DE

Inventors

Waldemar Pfrengle · Seibersbach, DE
Markus Frank · Baden-Baden, DE
Thomas KLEIN · Radolfzell, DE

Key dates

Filing date	Jul 13, 2012
Grant date	Nov 11, 2014
Priority date	—
Expiry date	Jul 13, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D473/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to substituted quinazolines of formula (I):wherein X and Y are defined as in claim 1, the tautomers, stereoisomers, mixtures and salts thereof, which have valuable pharmacological properties, particularly an inhibitory effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.