Patent · US Active

Preparation of (R)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide and (S)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide

US8884058B2 · kind B2 · utility

1Cited by

4References

8Claims

0Family size

Assignee

Ardea Biosciences, Inc · US

Inventors

Andreas Maderna · Stony Point, US
Jean-Michel Vernier · Laguna Niguel, US

Key dates

Filing date	Apr 23, 2013
Grant date	Nov 11, 2014
Priority date	—
Expiry date	Apr 23, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2601/02
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to the preparation of (R)—N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide and (S)—N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.