Modular nanoparticles for adaptable vaccines
US8889117B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 15, 2008 |
| Grant date | Nov 18, 2014 |
| Priority date | — |
| Expiry date | May 24, 2028 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Modular nanoparticle vaccine compositions and methods of making and using the same have been developed. Modular nanoparticle vaccine compositions comprise an antigen encapsulated in a polymeric particle and adaptor elements which modularly couple functional elements to the particle. The modular design of these vaccine compositions, which involves flexible addition and subtraction of antigen, adjuvant, immune potentiators, molecular recognition and transport mediation elements, as well as intracellular uptake mediators, allows for exquisite control over variables that are important in optimizing an effective vaccine delivery system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.