Patent · US Active

Crystal metabolite recovery

US8889395B2 · kind B2 · utility

0Cited by

1References

12Claims

0Family size

Assignee

Novozymes A/S · DK

Inventors

Peter Frode Pind · Copenhagen, DK
Simon Glanville · Kalundborg, DK
Sune Jakobsen
Svend Kaasgaard · Skovlunde, DK

Key dates

Filing date	Mar 25, 2011
Grant date	Nov 18, 2014
Priority date	—
Expiry date	Mar 25, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K1/306
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method for producing a crystalline and/or amorphous metabolite suspension from a cell fermentation broth in a continuous centrifuge process comprising (a) adding at a separate inlet to the centrifuge the fermentation broth comprising the cells and the metabolite of interest, wherein the metabolite is partly or wholly on crystalline and/or amorphous form; (b) adding at another inlet to the centrifuge an aqueous liquid comprising a salt and/or a carbohydrate having a higher density than the cells and a lower density than the metabolite of interest in its precipitated form; (c) removing the cells at a separate outlet to the centrifuge; and (d) removing the suspension comprising the crystalline and/or amorphous metabolite of interest at another outlet to the centrifuge.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.