Patent · US Active

Bioreactor for engineered tissue

US8889403B2 · kind B2 · utility

0Cited by
7References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 12, 2011
Grant dateNov 18, 2014
Priority date
Expiry dateJun 18, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12M33/00
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A system for generating a tissue construct includes a mixing chamber, a piston chamber, a reaction chamber, and a pump. The mixing chamber is configured to receive a hydrogel solution and a cell suspension solution. The piston chamber includes a first piston and is configured to receive a mixture of the hydrogel solution and the cell suspension solution from the mixing chamber. The first piston is configured to push the mixture through one or more capillaries into the reaction chamber. The reaction is configured to receive the mixture and a cross-linking initiator. The pump is configured to move the mixture through the reaction chamber such that the mixture and the cross-linking initiator combine to form an encapsulated cell material.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.