Patent · US Active

Stabilized p53 peptides and uses thereof

US8889632B2 · kind B2 · utility

51Cited by

104References

25Claims

0Family size

Assignees

DANA-FARBER CANCER INSTITUTE, INC. · US
President and Fellows of Harvard College · US

Inventors

Federico Bernal · Brookline, US
Loren D. Walensky · Newton, US
Gregory L. Verdine · Boston, US
Stanley J. Korsmeyer · Chesterfield, US

Key dates

Filing date	Jan 31, 2008
Grant date	Nov 18, 2014
Priority date	—
Expiry date	Dec 3, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Cross-linked peptides related to human p53 and bind to HMD2 or a family member of HDM2 useful for promoting apoptosis, e.g., in the treatment of and identifying therapeutic agents that binding to HMD2 or a family member of HDM2.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.