Patent · US Active

Composition containing antisense oligonucleotide to micro RNA

US8889649B2 · kind B2 · utility

1Cited by

0References

13Claims

0Family size

Assignee

National University Corporation Ehime University · JP

Inventors

Koichi Nakashiro · Ozu, JP
Hiroyuki Hamakawa · Nara, JP
Hiroshi Tanaka · Sakai, JP

Key dates

Filing date	Nov 10, 2011
Grant date	Nov 18, 2014
Priority date	—
Expiry date	Nov 10, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2330/31
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided is a composition that contains an antisense oligonucleotide to a micro RNA and is capable of inhibiting the growth of cancer cells. The present invention, as one aspect, relates to a composition for suppressing the growth of human cancer cells, the composition containing an antisense oligonucleotide to a micro RNA, wherein the micro RNA is selected from the group consisting of hsa-miR-133a, hsa-miR-133b, hsa-miR-346 and hsa-miR-361-3p. The present invention, as another aspect, relates to a composition for suppressing the growth of human head/neck cancer cells, the composition containing an antisense oligonucleotide to a micro RNA, wherein the micro RNA is selected from the group consisting of hsa-miR-92a, hsa-miR-133a, hsa-miR-133b, hsa-miR-139-5p, hsa-miR-197, hsa-miR-328, hsa-miR-346, hsa-miR-361-3p, hsa-miR-605, hsa-miR-766, hsa-miR-1228, hsa-miR-1252, hsa-miR-1260 and hsa-miR-1271.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.