Patent · US Active

C-17 bicyclic amines of triterpenoids with HIV maturation inhibitory activity

US8889854B2 · kind B2 · utility

1Cited by

7References

18Claims

0Family size

Assignee

Bristol-Myers Squibb Company · US

Inventors

Ny Sin · East Hampton, US
Zheng Liu · Beacon Falls, US
Jacob Swidorski · Wallingford, US
Sing-Yuen Sit · Meriden, US
Jie Chen · Houston, US
Yan Chen · Foster City, US
Nicholas A. Meanwell · East Hampton, US
Alicia Regueiro-Ren · Wallingford, US

Key dates

Filing date	Mar 13, 2013
Grant date	Nov 18, 2014
Priority date	—
Expiry date	Mar 20, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07J63/008
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 bicyclic amines of triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III:These compounds are useful for the treatment of HIV and AIDS.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.