Galliated calcium phosphate biomaterials
US8894958B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 3, 2010 |
| Grant date | Nov 25, 2014 |
| Priority date | — |
| Expiry date | Feb 1, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC04B2111/00836
- WIPO fieldMaterials, metallurgy
- WIPO sectorChemistry
Abstract
The present invention relates to a galliated calcium-phosphate biomaterial comprising a gallium-doped phosphocalcic compound of formula (I):Ca(10.5-1.5x)Gax(PO4)7 (I)wherein 0<x<1 and the salts, hydrates and mixtures thereof and/or a calcium deficient apatite structure with in particular a (Ca+Ga)/P molar ratio in the range of 1.3 to 1.67, and a gallium content up to 4.5% by weight.It also relates to processes of preparation of such materials and uses thereof, in particular as dental or bony implants.It further relates to a kit comprising a galliated calcium-phosphate biomaterial in combination with a fluid component.It finally relates to methods of use of the galliated calcium-phosphate biomaterial, notably for III) ions increase radio-opacity after bone implantation and can be released for inhibiting bone resorption.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.