Nitric oxide-releasing polymers
US8894985B2 · kind B2 · utility
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73References
20Claims
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Key dates
| Filing date | Nov 5, 2010 |
| Grant date | Nov 25, 2014 |
| Priority date | — |
| Expiry date | Feb 7, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G64/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequence nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.