Method for the treatment of amyloidoses

US8895004B2 · kind B2 · utility

Assignee

• Abb Vie Deutschland Gmbh & Co. KG · DE

Inventors

• Volker Nimmrich · Heidelberg, DE
• Stefan Barghorn · Mannheim, DE
• Ulrich Ebert · Mannheim, DE
• Heinz Hillen · Herbrechtingen, DE
• Gerhard Gross · Speyer, DE
• Andreas Draguhn · Heidelberg, DE
• Claus Bruhl · Schongau, DE
• Christine Grimm · Rielasingen-Worblingen, DE
• Carsten Krantz · Mannheim, DE

Key dates

• Filing date: Feb 27, 2008
• Grant date: Nov 25, 2014
• Expiry date: Oct 7, 2028

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K39/3955
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a method for the treatment of an amyloidosis such as Alzheimer's disease in a subject in need thereof, characterized in that it comprises administering an inhibitor of the interaction between Aβ globulomer and the P/Q type voltage-gated presynaptic calcium channel to said subject.