Methods for joint lubrication and cartilage wear prevention making use of glycerophospholipids
US8895054B2 · kind B2 · utility
4Cited by
6References
17Claims
0Family size
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Key dates
| Filing date | Mar 26, 2009 |
| Grant date | Nov 25, 2014 |
| Priority date | — |
| Expiry date | Sep 12, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention concerns methods of joint lubrication and/or prevention of cartilage wear making use of liposomes having membranes with at least one phospholipid (PL) of the group consisting of a glycerophospholipid (GPL) having two, being the same or different, C12-C16 hydrocarbon chain and a sphingolipid (SPL) having a C12-C15 hydrocarbon chain, the one or more membranes having a phase transition temperature in which solid ordered (SO) to liquid disordered (LD) phase transition occurs, the phase transition temperature being within a temperature of about 20° C. to about 39° C. for lubrication of joints.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.