Patent · US Active

Methysergide derivatives

US8895743B2 · kind B2 · utility

14Cited by
78References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 19, 2013
Grant dateNov 25, 2014
Priority date—
Expiry dateDec 19, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D457/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are novel methysergide derivatives and compositions thereof. In other embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders or symptoms thereof, such as, migraine and Parkinson's disease using the compounds and compositions disclosed herein. In still other embodiments, provided herein, such as, for example, are methods for antagonizing the 5-HT2B receptor without agonizing the 5-HT2B receptor using the compounds and compositions disclosed herein. In still other embodiments, provided herein such as, for example, are methods of agonizing the 5-HT1A receptor using the compounds and compositions disclosed herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.