Brain phosphorus spectroscopy in bipolar disorder
US8897854B2 · kind B2 · utility
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Key dates
| Filing date | Oct 16, 2012 |
| Grant date | Nov 25, 2014 |
| Priority date | — |
| Expiry date | May 11, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/4076
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Described herein are systems and methods of identifying bipolar disorder in a person. One such method includes acquiring 31P spectroscopic imaging data from a region of interest in a brain of the person and subsequently analyzing the 31P spectroscopic imaging data to obtain a signal intensity and a concentration for one or more phosphorus metabolites. A reduced concentration the one or more phosphorus metabolites, such as inorganic phosphate, in the brain can indicate bipolar disorder in the person. Frontal lobe inorganic phosphate concentration in medication-free adolescents can indicate bipolar depression.
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