Protein constructs designed for targeting and lysis of cells
US8900592B2 · kind B2 · utility
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3References
8Claims
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Assignee
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Key dates
| Filing date | Nov 23, 2006 |
| Grant date | Dec 2, 2014 |
| Priority date | — |
| Expiry date | Aug 28, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/735
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a protein construct, comprising (i) a targeting moiety that is capable of binding to a target cell, and (ii) an effector immunogenic moiety that is capable of triggering an existing, vaccine-induced or natural, immune response. The protein construct, that is preferably in the form of a heteromultimeric protein, is useful for redirecting an immune response that was pre-existing in a patient, toward an undesired target cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.