Patent · US Active

Oral recombinant Helicobacter pylori vaccine and preparing method thereof

US8900594B2 · kind B2 · utility

0Cited by

2References

10Claims

0Family size

Assignee

Wuhu Kangwei Biotechnology Co., Ltd · CN

Inventors

Quanming Zou · Chongqing, CN
Wende Tong · Shanguang, CN
Xuhu Mao · Shanguang, CN
Gang Guo · Bositenghu, CN
Dongshui Lu · Shanguang, CN
Chao Wu · Shanguang, CN
Hao Zeng · Chongqing, CN
Yichao Wang · Shanguang, CN
Jun Yang · Beijing, CN
Weijun Zhang · Nanhu, CN
Kaiyun Liu · Shanguang, CN
Ping Luo · Sha Tin, CN

Key dates

Filing date	Sep 5, 2007
Grant date	Dec 2, 2014
Priority date	—
Expiry date	Jul 30, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/55
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a recombinant protein used for immunoprophylaxis of human Helicobacter pylori infection and a degradable slow-releasing microsphere-encapsulated oral vaccine preparation prepared from the same, and the preparation method thereof. Said recombinant protein is composed of A2 subunit and B subunit of the LT of enterotoxigenic Escherichia coli and urease B subunit. The vaccine provided in the invention used in human Helicobacter pylori infection is safe and effective and convenient for oral intake.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.