Process for producing optically active succinimide derivatives
US8900830B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Jul 28, 2011 |
| Grant date | Dec 2, 2014 |
| Priority date | — |
| Expiry date | Jul 28, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/005
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for efficiently producing optically active succinimide derivatives as key intermediates of (3R)-2′-(4-bromo-2-fluorobenzyl)spiro{pyrrolidine-3,4′(1′H)-pyrrolo[1,2-a]pyrazine}-1′,2,3′,5(2′H)-tetraone, which comprises the following reaction steps, and the step 2 is performed by using a non-animal-derived enzyme.
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