Patent · US Active

Selective inhibition of polyglutamine protein expression

US8901095B2 · kind B2 · utility

8Cited by

12References

27Claims

0Family size

Assignee

The Board of Regents of the University of Texas System · US

Inventors

David R. Corey · Dallas, US
Jiaxin Hu · Coppell, US
Masayuki Matsui · Osaka, JP

Key dates

Filing date	Jul 28, 2009
Grant date	Dec 2, 2014
Priority date	—
Expiry date	Dec 12, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2310/3231
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to the selective inhibition of protein expression of CAG repeat-related disease proteins such as Huntingtin using nucleic acid analogs. Peptide nucleic acids and locked nucleic acids are particularly useful analogs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.