Patent · US Active

Neprilysin inhibitors

US8901169B2 · kind B2 · utility

15Cited by
26References
31Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 4, 2014
Grant dateDec 2, 2014
Priority date
Expiry dateMar 4, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/16
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

In one aspect, the invention relates to compounds having the formula:where R1-R5 and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.