Method for synthesizing 3,5-dichloroanisole from 1,3,5-trichlorobenzene
US8901361B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 12, 2011 |
| Grant date | Dec 2, 2014 |
| Priority date | — |
| Expiry date | Jan 12, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C209/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for synthesizing 3,5-dichloroanisole from 1,3,5-trichloro-benzene is proved. The method may comprises: a) the reaction between 1,3,5-trichloro-benzene and a methanolate of an alkaline or alkaline-earth metal in a first solvent chosen from among dimethylsulfoxide and 1,1,3,3-tétramethylurea, b) the precipitation of the product resulting from step a) in a second solvent which is not included among substances considered carcinogenic, mutagenic and/or toxic for reproduction by Regulation (EC) no 1272/2008 of the European Parliament and of the Council of 16 Dec. 2008, then c) the recovery of the precipitate thus obtained. The method may be applied to synthesize 1,3,5-triamino-2,4,6-trinitrobenzene in which 3,5-dichloroanisole is an intermediate product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.