Systems and methods for delivering substances into nanoporous mineralized tissues
US8905759B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 8, 2012 |
| Grant date | Dec 9, 2014 |
| Priority date | — |
| Expiry date | Jun 8, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/306
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods and systems are provided for transporting a therapeutic or cosmetic substance into nanoporous mineralized tissue structures, such as teeth. The method may include contacting the nanoporous mineralized tissue structure with an ionic solution including the therapeutic or cosmetic substance; and simultaneously applying to the nanoporous mineralized tissue structure an electrical potential effective to transport the therapeutic or cosmetic substance into the nanopores of the nanoporous mineralized tissue structure. The system may include at least one pair of electrodes which includes a first electrode configured for contacting the nanoporous mineralized tissue structure and a second electrode; and a power source and control circuitry for generating an electrical potential between the first electrode and the second electrode effective to transport a therapeutic or cosmetic substance, in an ionic solution in contact with a surface of the nanoporous mineralized tissue structure, into the nanopores of the nanoporous mineralized tissue structure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.