Using phylogenetic probes for quantification of stable isotope labeling and microbial community analysis
US8906610B2 · kind B2 · utility
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Key dates
| Filing date | Feb 8, 2011 |
| Grant date | Dec 9, 2014 |
| Priority date | — |
| Expiry date | Feb 8, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6837
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Herein is described methods for a high-sensitivity means to measure the incorporation of stable isotope labeled substrates into RNA following stable isotope probing experiments (SIP). RNA is hybridized to a set of probes such as phylogenetic microarrays and isotope incorporation is quantified such as by secondary ion mass spectrometer imaging (NanoSIMS).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.