Methods for sequencing individual nucleic acids under tension

US8906617B2 · kind B2 · utility

Assignee

• Life Technologies Corporation · US

Inventors

• Jonathan M. Rothberg · Paradise, US
• John Leamon · Norwick, GB
• John F. Davidson · Guilford, US
• Antoine M. van Oijen · Needham, US
• Wolfgang Hinz · Killingworth, US
• Melville Davey · Swansea, US
• Bradley Hann · Sierra Vista, US
• Jonathan Schultz · Guilford, US

Key dates

• Filing date: Mar 9, 2011
• Grant date: Dec 9, 2014
• Expiry date: Mar 9, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2523/303
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention provides apparatuses and methods of use thereof for sequencing nucleic acids subjected to a force, and thus considered under tension. The methods may employ but are not dependent upon incorporation of extrinsically detectably labeled nucleotides.