Fed-batch method of making human anti-TNF-alpha antibody
US8906646B2 · kind B2 · utility
42Cited by
68References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 26, 2014 |
| Grant date | Dec 9, 2014 |
| Priority date | — |
| Expiry date | Mar 26, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2511/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.