Antibiotic compositions for the treatment of gram negative infections
US8906866B2 · kind B2 · utility
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Key dates
| Filing date | Mar 15, 2013 |
| Grant date | Dec 9, 2014 |
| Priority date | — |
| Expiry date | Mar 15, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/19
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are novel compounds and novel protected compounds that can be derived from polymyxin, including, e.g., polymyxin A. The novel compounds have antibacterial properties against a diverse range of Gram negative bacteria and reduced toxicity compared to polymyxins such as polymyxin A. Also provided are antibacterial pharmaceutical compositions containing the novel compounds and novel protected compounds, as well as methods for preparing the antibacterial compounds and protected compounds.
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