Low-calcemic 16,23-diene 25-oxime analogs of 1α,25-dihydroxy vitamin D3
US8906888B2 · kind B2 · utility
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23Claims
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Key dates
| Filing date | Apr 25, 2006 |
| Grant date | Dec 9, 2014 |
| Priority date | — |
| Expiry date | Nov 6, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel 16,23-diene 25-oxime ether analogs of 1,25-dihydroxy vitamin D3, compositions comprising these compounds and methods of using these compounds as inhibitors of CYP24. In particular, the novel compound of the invention are useful for treating diseases which benefit from a modulation of the levels of 1,25-dihydroxy vitamin D3, for example, cell-proliferative disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.