Inhibitors of bacterial type III secretion system
US8906945B2 · kind B2 · utility
2Cited by
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7Claims
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Key dates
| Filing date | Apr 6, 2010 |
| Grant date | Dec 9, 2014 |
| Priority date | — |
| Expiry date | Jul 30, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Organic compounds showing the ability to inhibit effector toxin secretion or translocation mediated by bacterial type III secretion systems are disclosed. The disclosed type III secretion system inhibitor compounds are useful for combating infections by Gram-negative bacteria such as Salmonella spp., Shigella flexneri, Pseudomonas spp., Yersinia spp., enteropathogenic and enteroinvasive Escherichia coli, and Chlamydia spp. having such type III secretion systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.