Cytometry system with solid numerical-aperture-increasing lens
US8907312B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 18, 2011 |
| Grant date | Dec 9, 2014 |
| Priority date | — |
| Expiry date | Jul 4, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6421
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A flow cytometry system includes a flow element through which a cell is transported in a flowing fluid. The flow element includes a bore bounded by a wall. A light source is configured to illuminate the cell. An optical system receives light emanating from the cell and directs at least some of the received light to a light sensor. The optical system includes a numerical-aperture-increasing lens at a wall of the flow element. At least some of the received light passes through the numerical-aperture-increasing lens. The flow cytometry system may also include a beam splitter that directs two wavelength bands of the emanating light such that light in two wavelength band preferentially reach different sensing locations via different paths. The system may also include an optical element placed in one of the paths, shifting a focal location of the affected path to compensate for chromatic aberration of the numerical-aperture-increasing lens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.